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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP2
All Species:
22.73
Human Site:
S424
Identified Species:
38.46
UniProt:
P46087
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46087
NP_001028886.1
812
89302
S424
A
N
A
E
R
L
K
S
V
V
G
N
L
H
R
Chimpanzee
Pan troglodytes
XP_001162276
812
89269
S424
A
N
A
E
R
L
K
S
V
V
G
N
L
H
R
Rhesus Macaque
Macaca mulatta
XP_001105884
811
89266
S423
A
N
A
E
R
L
K
S
V
V
G
N
L
H
R
Dog
Lupus familis
XP_854432
985
108067
S595
A
N
A
E
R
L
K
S
V
V
G
N
L
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q922K7
793
86733
S409
A
N
A
D
R
L
K
S
V
V
G
N
L
H
R
Rat
Rattus norvegicus
XP_235295
772
84951
S404
A
N
A
E
R
L
K
S
V
V
G
N
L
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416502
682
76182
L329
R
R
D
L
A
Q
A
L
I
N
R
G
V
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922354
739
83513
A355
D
S
S
V
P
I
G
A
T
P
E
Y
L
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610786
891
99823
A475
S
N
R
D
R
I
K
A
I
V
A
N
F
H
R
Honey Bee
Apis mellifera
XP_001121968
582
67009
I229
R
I
K
D
I
V
M
I
L
S
D
F
K
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787141
1076
119756
A701
A
N
K
K
R
V
S
A
L
V
G
N
L
H
R
Poplar Tree
Populus trichocarpa
XP_002300386
476
53332
N123
D
L
A
N
V
L
L
N
R
G
V
N
L
D
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194390
671
75524
E318
V
P
I
G
A
T
P
E
Y
L
A
G
F
Y
M
Baker's Yeast
Sacchar. cerevisiae
P40991
618
69794
A264
E
A
M
E
F
F
E
A
N
E
I
A
R
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
68.8
N.A.
75.8
75.1
N.A.
N.A.
55.5
N.A.
53
N.A.
41
37.5
N.A.
37.4
Protein Similarity:
100
99.3
96.1
73.8
N.A.
83.2
82
N.A.
N.A.
65.3
N.A.
66.5
N.A.
57.6
49.2
N.A.
49.7
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
0
N.A.
6.6
N.A.
46.6
0
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
N.A.
33.3
N.A.
80
20
N.A.
86.6
Percent
Protein Identity:
37.9
N.A.
N.A.
39.7
37.4
N.A.
Protein Similarity:
47.6
N.A.
N.A.
55.6
52
N.A.
P-Site Identity:
26.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
8
50
0
15
0
8
29
0
0
15
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
22
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
0
0
43
0
0
8
8
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
8
15
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
0
8
50
15
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% H
% Ile:
0
8
8
0
8
15
0
8
15
0
8
0
0
0
8
% I
% Lys:
0
0
15
8
0
0
50
0
0
0
0
0
8
0
0
% K
% Leu:
0
8
0
8
0
50
8
8
15
8
0
0
65
0
15
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
58
0
8
0
0
0
8
8
8
0
65
0
8
0
% N
% Pro:
0
8
0
0
8
0
8
0
0
8
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
8
8
0
58
0
0
0
8
0
8
0
8
8
58
% R
% Ser:
8
8
8
0
0
0
8
43
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
8
8
15
0
0
43
58
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _